Current Clinical Drug Trials for Hepatitis C In New Zealand
New Zealand has up to six different drug trials currently in progress for Hepatitis C.
1 Recruiting TMC435-TiDP16-C205: A Phase II Study of TMC435 in Combination With Pegylated Interferon Alpha-2a and Ribavirin in Patients Infected With Genotype 1 Hepatitis C Virus Who Never Received Treatment
Condition: Hepatitis C
Interventions: Drug: PegIFNalpha-2a; Drug: PegIFNalpha-2a; Drug: Ribavirin PegIFNalpha-2a; Drug: Ribavirin PegIFNalpha-2a; Drug: TMC435 TMC435 Placebo; Drug: TMC435 Ribavirin; Drug: TMC435 TMC435 Placebo; Drug: TMC435 Ribavirin; Drug: PegIFNalpha-2a; Drug: TMC435 Placebo Ribavirin
2 Recruiting A Study of Combination Treatment With an HCV Polymerase Inhibitor (Polymerase Inhibitor) and an HCV Protease Inhibitor (RO5190591) in Genotype 1 Chronic Hepatitis C Patients
Condition: Hepatitis C, Chronic
Interventions: Drug: RO5024048/RO5190591; Drug: RO5024048/RO5190591; Drug: RO5024048/RO5190591; Drug: RO5024048/RO5190591; Drug: RO5024048/RO5190591; Drug: RO5024048/RO5190591
3 Recruiting Safety and Efficacy of MK7009 Administered With Pegylated Interferon (Peg-IFN) and Ribavirin (RBV)
Condition: Chronic Hepatitis C Virus Infection
Interventions: Drug: Comparator: Peg-INF; Drug: Comparator: RBV; Drug: Comparator: MK7009;; Drug: Comparator: Placebo.; Drug: Comparator: MK7009.; Drug: Comparator: MK7009; Drug: Comparator: Placebo;; Drug: Comparator: Peg-INF.; Drug: Comparator: RBV.
4 Recruiting Safety and Tolerability Study of Clemizole Hydrochloride to Treat Hepatitis C in Subjects Who Are Treatment-Naive
Condition: Hepatitis C
Intervention: Drug: clemizole hydrochloride
5 Recruiting Antiviral Activity of AZD7295 in HCV Carriers
Condition: Hepatitis C
Interventions: Drug: AZD7295; Drug: Placebo
6 Recruiting Drug-Drug Interaction Study of VCH-222 and Telaprevir in Healthy Subjects
Condition: Hepatitis C
Interventions: Drug: VCH-222; Drug: VCH-222; Drug: VCH-222; Drug: telaprevir
Interesting to discover so many trials underway in New Zealand and these are just the current ones. I guess if you want to get on a drug trial you are chosen as opposed to applying in most cases, but its all ways worth asking your medical provider about them.
You can read more detail at this informative site
www.ClinicalTrials.gov
ClinicalTrials.gov United States National Institutes of Health offers up-to-date information for locating federally and privately supported clinical trials for a wide range of diseases and conditions. A clinical trial (also clinical research) is a research study in human volunteers to answer specific health questions. Interventional trials determine whether experimental treatments or new ways of using known therapies are safe and effective under controlled environments. Observational trials address health issues in large groups of people or populations in natural settings.
When drug trials go Bad
Whenever I think of drug trials I think of guinea pigs and the tragic British drug trials of March 2006, A case of guinea pig beware I guess.
“It was the first time the drug TBN1412, designed to treat conditions such as rheumatoid arthritis and leukaemia, had been tested on humans.
Within hours of taking it on Monday, the six young volunteers had to be admitted to intensive care.
Ms Marshall, 35, whose boyfriend is critically ill, said the normally healthy 28-year-old’s face was so puffed, he “looks like the Elephant Man”.
She said he was completely lifeless, unable even to move an eyelid.
“They just keep saying he’s very, very sick and we are doing all we can,” she added. “
Such clinical trials were essential for the development of new and better treatments
The Medical Research Council said that while it was “an unfortunate and extremely rare event”, such clinical trials were essential for the development of new and better treatments.”
http://news.bbc.co.uk/2/hi/uk_news/england/london/4808836.stm
Best of Heath www.hcv.org.nz